5 Reasons Your Psoriasis Treatment Isn’t Working

By Leah Campbell
Reviewed by Allison Truong, M.D.
May 03, 2022

Any time you start a psoriasis treatment plan, you probably have a feeling of hope. You’re ready to find relief and optimistic that this treatment will get you there. So when it doesn’t, it’s normal to experience frustration and feelings of defeat. Not to mention how you may feel if a treatment that has previously worked suddenly stops being effective—likely, all those same negative feelings can come flooding back.

“There are numerous reasons your psoriasis may be resistant to treatment,” says board-certified dermatologist Scott Paviol, M.D., of PHC Paviol Dermatology in Charlotte, North Carolina. “First, you want to make sure you have the correct diagnosis from your doctor, that both of you are confident in.”

If there’s any doubt whether you have psoriasis, your doctor may want to confirm the diagnosis with a skin biopsy, Paviol says. If it’s definitely psoriasis and your treatments aren’t working, there may be several potential explanations—plus, plenty of alternative treatment options you can try to get the relief you deserve.

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