When you have an inflammatory condition, such as psoriasis or psoriatic arthritis, biologic medications can work wonders to calm inflammation, reduce symptoms, and prevent further joint damage.

Biologics have revolutionized treatment, says Stuart Kaplan, M.D., chief of rheumatology at Mount Sinai South Nassau Hospital in Oceanside, New York, and partner at Rheumatology Consultants, LLC. Instead of targeting the entire immune system, like traditional systemic medications do, biologics target specific immune pathways, making them effective and less likely to cause side effects.

But this type of disease-modifying anti-rheumatic drug (DMARD) often comes with a hefty pre-insurance price tag. Here, experts share why biologics are so expensive and strategies to help you afford this treatment, if it’s right for you.