When it comes to treating psoriasis, tackling uncomfortable itchy, scaly patches on your skin is usually top of mind. But it’s equally important to control any psoriasis-related inflammation in the body. Fighting inflammation may not only alleviate symptoms, but may also help prevent the disease from progressing as well as prevent psoriasis-related health complications.

Together, you and your doctor should create a personalized treatment plan, which will depend on the severity of your disease, any related health issues and health risk factors you may have, as well as your personal preferences. Understanding your options will help you make an informed decision. There are four main categories of psoriasis medications, which differ in how they’re administered and how they work—as well as in their benefits and risks. Here’s what you should know about each type.

Topicals

Topical therapies are medications applied directly to the skin to help tame inflammation and soothe psoriasis symptoms.